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29 de septiembre de 2022

Absolute Dose Definition

Effective dose: The amount of the effective dose helps us to take into account sensitivity. There are several amounts in which the dose is measured (for example, mGy, mSv). There are other dose amounts that have not been discussed. Energy dose and equivalent dose measurements can be used to assess short-term risk to tissues. (In the short term, weeks or months ago.) The amount determined by the Fricke chemical dosimetry system is the energy dose for the Fricke solution (DF) as defined in equation (7) and described in the literature by [19, 20]. fw,F= factor that converts the energy dose for Fricke`s solution into the energy dose for water. Measurements of quantity Exposure due to air kerma is of great importance, as they represent the inserts of the metrological chain. They are directly related to the calibrations of the energy doses of high-energy photon and electron beams used in radiotherapy, radiobiology studies and radiation protection measures; the latter is for the moment completely dependent on the amount of kerma air. kt = transient effect on thermistor response due to dose deposition; If you have a CT scan of your upper abdomen, the absorbed dose to your breast is very low because it has only been exposed to a small amount of diffuse radiation. The absorbed dose for your stomach, pancreas, liver and other organs is the most important because they have been directly exposed. For patients, the most important dose amount is the effective dose, as it makes it easy to compare long-term risks.

These measurements are carried out in the user`s installation with his reference chamber to obtain the energy dose for the water with a jet of the same quality as the SSDL under the reference conditions: SSD = 100 cm, radiation field 10 x 10 cm2 and depth of 5 cm in the water according to the Eq. (10): Fricke dosimetry consists of the measurement of the conversion, due to the ionizing radiation of the iron ions present in the solution into iron ions by spectrophotometry. The Fricke dosimeter consists of a 96% water solution, so its attenuation against radiation is very similar to that of water and can be used in the dose range of 5 Gy-400 Gy with dose rates of up to 106 Gy / s. The clinical results of different institutions can be comparable if the air-kerma dose or energy, in addition to the biological clinical parameters, is well known and fully described. The most important steps in the conversion of quantities: (a) kerma of air and (b) absorbed dose into water. Very high dose per pulse (3-13 cGy/pulse) High-energy electron beams are currently generated by special linear accelerators (linac) dedicated to intraoperative radiotherapy (IORT). The electron beams generated by these linacs are collimated by special plexiglass applicators of different sizes and cylindrical shape. The biggest problems from a dosimetric point of view are caused by the high dose values per pulse and the use of inclined applicators.

In this work, absolute dose measurements for the inclined applicators were made using a small cylindrical ionization chamber, cc01 type (Wellhofer), a markus-type parallel plane ionization chamber (PTW 23343) and EBT-type radiochromic films. We show a method that allows to calculate the quality correction factors for the CC01 chamber with an uncertainty of 1% and the absolute dose value for inclined applicators using CC01 with an uncertainty of 3.1% for the electron beams of energy of 6 and 7 MeV generated by the Linac dedicated to IORT Novac7. This is the measurement of the energy dose in the water with an ionization chamber in the jet of the user`s institution. The reference conditions used in the calibration laboratory shall be reproduced and the influence variables (T, P, U) shall be measured accordingly at the time of data acquisition and correction. At this point, it is necessary to emphasize the importance of a network called the International Metrological Network, which essentially aims to standardize processes and methods between the different laboratories of the world. As a result, the measurement of the main amounts of interest for radiotherapy, radiology and radiation protection such as air kerma and energy dose in water allows a scientific comparison of clinical results and biological effects between different users, with an acceptable level of uncertainty for each area. When instruments of the highest metrological quality are used, the quantities are measured according to their definition, i.e. absolutely. Achieving this level requires highly sophisticated equipment, computer control systems, experimental devices and highly qualified personnel, resulting in very low uncertainties, results that cannot be replicated in the end-user`s environment.

A dosimetric procedure aims to estimate a quantity to ensure the delivery of the correct prescribed dose to a patient or the dose resulting from a diagnostic procedure. The effective dose is a calculated value, measured in mSv, which takes into account three factors: the equivalent dose is an amount that takes into account the harmful properties of different types of radiation. (Not all radiation is created equal.) These laboratories use open-air chambers for air kerma standards in low- and medium-energy X-rays; water or graphite calorimeters for the dose of water or graphite energy; The Fricke dosimeter is a standard for the energy dose of water and ionization chambers with a volume known as the standard for air kerma for gamma rays emitted by a collimated 60Co, or for absorbed dose for graphite using a variety of photons and electron beams. It is the measurement of a quantity with an instrument of the highest metrological quality, which allows its determination according to its definition. In general, it is carried out in primary laboratories. For properly performed diagnostic examinations, there are no short-term effects of radiation exposure, so the energy dose and equivalent dose are not very useful.